Weile, Karmin has flown at least 8 times. I would never fly her without the sedative, she'd kill herself before the plane took off trying to get out and beat on the metal door. Without the sedative she bangs on the kennel and metal door and her paws start bleeding before she's even on the plane. I assume she'd be more likely to hurt herself if not on the sedative. The sedative should not increase the risk of fatalities. In fact both of my vets highly recommend Karmin taking it. I could not imagine my Karmin having to travel 12 hours without it. Honestly being in that small box if there was an emergency there is nothing she could do about it whether she was drosey or fully alert, but I don't even want to think about this topic or discuss it further.
As for American, I have flown her numerous times and they have no problem with my dog being on a sedative.
Thanks again Cheryl.
AmbergrisCaye.com 
